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KMID : 0606620090050010003
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Korean Journal of Fetal Medicine
2009 Volume.5 No. 1 p.3 ~ p.10
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First and Second Trimester Ultrasonogram for Detection of Fetal Down syndrome
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Jeoung Hyo-Young
Choi Sang-Joon
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Abstract
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Most women undergo screening test for detection of the fetal Down syndrome. The genetic sonogram that evolved in the mid-1990s has been utilized as a method to help women decide about the need for amniocentesis after maternal serum biochemistry. Definitely, the use of the genetic sonogram decreases the number of amniocentesis, but also reduces the detection rate of Down syndrome. There has been interest in screening method at first trimester and the recent trend of screening test for Down syndrome shifts to first trimester of pregnancy. We think that the effectiveness of genetic sonogram as a tool of screening for detection of Down syndrome should be refined. This review serves to recent researches of ultrasonogram for detection of fetal Down syndrome during first and second trimester of pregnancy.
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KEYWORD
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Down syndrome, Screening, Ultrasonogram, Genetic sonogram
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